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Human NMUR1/Galpha15 Stable Cell Line-Chem-1

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Cat.No.
CSC-RG0700
Background
Neuromedin U (NmU) is a peptide characterized by its ability to promote smooth muscle contraction. Two GPCRs, NMU1 and NMU2, mediate the contractile effects of neuromedin U by activation of both Gq and Gi. In addition, NmU binds to NMU1 expressed on Th2 cells to induce cytokine release.
Growth Properties
Adherent
Host Cell
Chem-1
Ship
Dry ice
Gene Information
Official Symbol
NMUR1
Synonyms
NMUR1; neuromedin U receptor 1; G protein coupled receptor 66 , GPR66; neuromedin-U receptor 1; FM 3; GPC R; NMU1R; NMU-R1; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; FM3; FM-3; GPC-R; GPR66; (FM-3);
Gene ID
MIM
UniProt ID
Q9HB89
Chromosome Location
2q37.1
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
G-protein coupled receptor activity; neuromedin U receptor activity; neuropeptide receptor activity; receptor activity; signal transducer activity;

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