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Human MTNR1B/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1553
Background
MT2 receptor, also known as MTNR1B (Melatonin receptor type 1B), is a high affinity receptor for melatonin. It is known to mediate the reproductive and circadian actions of melatonin and is considered as a novel therapeutic target for the development of subtype-selective analogs for the treatment of circadian sleep and mood-related disorders. MT2 receptor is also likely to mediate the interfering with the apoptotic pathway activated by heat shock in HL-60 cells.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
MTNR1B
Synonyms
MTNR1B; melatonin receptor 1B; melatonin receptor type 1B; mel1b receptor; melatonin receptor MEL1B; MT2; FGQTL2; MEL-1B-R;
Gene ID
MIM
UniProt ID
P49286
Chromosome Location
11q21-q22
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; melatonin receptor activity; receptor activity; signal transducer activity;

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