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Human MTNR1B/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0481
Background
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
MTNR1B
Synonyms
MTNR1B; melatonin receptor 1B; melatonin receptor type 1B; mel1b receptor; melatonin receptor MEL1B; MT2; FGQTL2; MEL-1B-R;
Gene ID
MIM
UniProt ID
P49286
Chromosome Location
11q21-q22
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; melatonin receptor activity; receptor activity; signal transducer activity;

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