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Human MC4R-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0297
Background
The melanocortin receptor MC4 is expressed in the central nervous system, gastrointestinal tract and placenta. The melanocortin family is essential in the control of body weight homeostasis, sexual behavior, and autonomic functions; MC4 receptors are primarily involved in the regulation of food uptake. MC4 agonists have great potential in the treatment of weight disorders and sexual dysfunction, whereas MC4 antagonists may be useful in the treatment of anorectic and cachectic conditions.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
MC4R
Synonyms
MC4R; melanocortin 4 receptor; melanocortin receptor 4; MC4-R; MGC126851; MGC138197;
Gene ID
MIM
UniProt ID
P32245
Chromosome Location
18q22
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; melanocortin receptor activity; melanocyte-stimulating hormone receptor activity; neuropeptide binding; peptide hormone binding; protein binding; receptor activity; signal transducer activity; ubiquitin protein ligase binding;

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