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Human MC3R Stable Cell Line-HEK293/CRE-Luc

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Cat.No.
CSC-RG1637
Background
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
Host Cell
HEK293/CRE-Luc
Ship
Dry Ice
Antigen Gene Information
Official Symbol
MC3R
Synonyms
MC3R; melanocortin 3 receptor; melanocortin receptor 3; MC3; Obesity quantitative trait locus; OB20; OQTL; BMIQ9; MC3-R;
GeneID
MIM
UniProt ID
P41968
Chromosome Location
20q13.2-q13.3
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; melanocortin receptor activity; melanocyte-stimulating hormone receptor activity; neuropeptide binding; peptide hormone binding; protein binding; receptor activity; signal transducer activity;

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