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Human MC2R Stable Cell Line-CHO-K1/Gα15

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Cat.No.
CSC-RG1683
Background
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.
Host Cell
CHO-K1/Gα15
Ship
Dry Ice
Antigen Gene Information
Official Symbol
MC2R
Synonyms
MC2R; melanocortin 2 receptor (adrenocorticotropic hormone); adrenocorticotropic hormone receptor; ACTHR; MC2 receptor; ACTH receptor; corticotropin receptor; adrenocorticotropin receptor; MGC125798;
GeneID
MIM
UniProt ID
Q01718
Chromosome Location
18p11.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; corticotropin receptor activity; melanocortin receptor activity; protein binding; receptor activity; signal transducer activity;

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