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Human LTB4R/Galpha15 Stable Cell Line-Chem-1

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Cat.No.
CSC-RG0679
Background
Leukotriene and related receptors are activated by the endogenous ligands leukotriene (LT) B4, LTC4, LTD4, LTE4 and 12-HETE. Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase enzymes. They act on peroxisome-proliferating receptors (PPARs) as well as the G-protein-coupled leukotriene receptors, and are important in inflammatory signaling pathways. Leukotriene and related receptors are high affinity stereoselective receptors that have a wide biological distribution. BLT1 and BLT2 receptors are synthesized by polymorphonuclear leukocytes and are found at their highest concentrations on myeloid cells, mast cells and macrophages.
Growth Properties
Adherent
Host Cell
Chem-1
Ship
Dry ice
Gene Information
Official Symbol
LTB4R
Synonyms
LTB4R; leukotriene B4 receptor; CMKRL1, GPR16, P2RY7; leukotriene B4 receptor 1; BLTR; LTB4R1; P2Y7; LTB4-R1; LTB4-R 1; P2Y purinoceptor 7; chemokine receptor-like 1; G protein-coupled receptor 16; G-protein coupled receptor 16; chemoattractant receptor-like 1; purinergic receptor P2Y, G-protein coupled, 7; BLT1; GPR16; LTBR1; P2RY7; CMKRL1;
Gene ID
MIM
UniProt ID
Q15722
Chromosome Location
14q11.2-q12
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Leukotriene receptors, organism-specific biosystem;
Function
leukotriene B4 receptor activity; leukotriene receptor activity; nucleotide binding; receptor activity; signal transducer activity;

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