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Human LPAR4-FLAG Stable Cell Line-CHO

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Cat.No.
CSC-RG0286
Background
Human LPA4 (also known as P2Y9 and GPR23) receptors are G protein-coupled receptors. The cDNA encodes a 370-amino-acid polypeptide. The LPA4 receptors are predominately expressed in ovary, and also present in kidney, skeletal muscle and other brain and peripheral tissues. In rat neuroblastoma cells overexpressing the receptors, LPA promotes neurite retraction and cell rounding indicating LPA4 may mediate morphological changes in neuronal cells. Studies in LPA4 knockout mice revealed a role of LPA4 in the negative control of cell migration.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
LPAR4
Synonyms
LPAR4; lysophosphatidic acid receptor 4; G protein coupled receptor 23 , GPR23; LPA4; P2RY9; P2Y5 LIKE; P2Y9; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23; GPR23; P2Y5-LIKE;
Gene ID
MIM
UniProt ID
Q99677
Chromosome Location
Xq21.1
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; LPA receptor mediated events, organism-specific biosystem; LPA4-mediated signaling events, organism-specific biosystem;
Function
G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; lipid binding; receptor activity; signal transducer activity;

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