Human LPAR4-FLAG Stable Cell Line-CHO

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Cat.No.

CSC-RG0286

Background

Human LPA4 (also known as P2Y9 and GPR23) receptors are G protein-coupled receptors. The cDNA encodes a 370-amino-acid polypeptide. The LPA4 receptors are predominately expressed in ovary, and also present in kidney, skeletal muscle and other brain and peripheral tissues. In rat neuroblastoma cells overexpressing the receptors, LPA promotes neurite retraction and cell rounding indicating LPA4 may mediate morphological changes in neuronal cells. Studies in LPA4 knockout mice revealed a role of LPA4 in the negative control of cell migration.

Growth Properties

Adherent

Morphology

Epithelial-like

Host Cell

CHO-K1

Ship

Dry ice

Gene Information

Gene Name

LPAR4 lysophosphatidic acid receptor 4 [ Homo sapiens ]

Official Symbol

LPAR4

Synonyms

LPAR4; lysophosphatidic acid receptor 4; G protein coupled receptor 23 , GPR23; LPA4; P2RY9; P2Y5 LIKE; P2Y9; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23; GPR23; P2Y5-LIKE;

Gene ID

2846

MIM

300086

UniProt ID

Q99677

Chromosome Location

Xq21.1

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; LPA receptor mediated events, organism-specific biosystem; LPA4-mediated signaling events, organism-specific biosystem;

Function

G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; lipid binding; receptor activity; signal transducer activity;

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