LPAR3,EDG7,Edg 7,HOFNH30,LP A3,LPA3,RP4 678I3,LPA-3,GPCR,Edg-7,LP-A3,RP4-678I3,FLJ98231
LPA and the structurally related lysophoslipid mediator sphingosine 1-phosphate (S1P) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g. EDG2) are LPA receptors. LPA3 receptor (EDG7) mediates responses preferentially to unsaturated LPA, whereas LPA2 receptor (EDG4) mediates responses to both saturated and unsaturated LPA.