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Human HTR7/Gs Stable Cell Line-U2OS

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Cat.No.
CSC-RG0574
Background
The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin. The 5-HT7 receptor is expressed in a variety of tissues, particularly in the brain, the gastrointestinal tract, and various blood vessels. The 5-HT7 receptor plays a role in smooth muscle relaxation within the vasculature and in the gastrointestinal tract, and
is involved in thermoregulation, circadian rhythm, learning and memory, and sleep. This receptor is also involved in mood regulation, suggesting that it may be a useful target in the treatment of depression.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
U2OS
Ship
Dry ice
Gene Information
Official Symbol
HTR7
Synonyms
HTR7; 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled); 5-hydroxytryptamine receptor 7; 5 HT7; 5-HT-7; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-HT7;
Gene ID
MIM
UniProt ID
P34969
Chromosome Location
10q21-q24
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; serotonin receptor activity; signal transducer activity;

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