HTR1B,5 HT1B,5 HT1DB,HTR1D2,S12,5-HT-1B,5-HT1B,HTR1DB,5-HT1DB,
The human serotonin receptor 5-HT1B is a G protein-coupled receptor. 5-HT1B receptors are present in many parts of the central nervous system, but most notably, can be found in the basal ganglia, striatum, and frontal cortex. 5-HT1B receptors inhibit the release of many neurotransmitters, such as serotonin, GABA, acetylcholine, and glutamate. 5-HT1B ligands may prove to be therapeutic in the treatment of various disorders such as depression, anxiety, and aggression.