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Human HTR1B/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0580
Background
The human serotonin receptor 5-HT1B is a G protein-coupled receptor. 5-HT1B receptors are present in many parts of the central nervous system, but most notably, can be found in the basal ganglia, striatum, and frontal cortex. 5-HT1B receptors inhibit the release of many neurotransmitters, such as serotonin, GABA, acetylcholine, and glutamate. 5-HT1B ligands may prove to be therapeutic in the treatment of various disorders such as depression, anxiety, and aggression.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
HTR1B
Synonyms
HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 1B; 5-hydroxytryptamine receptor 1B; 5 HT1B; 5 HT1DB; HTR1D2; S12; 5-HT-1B; 5-HT-1D-beta; serotonin receptor 1B; serotonin 1D beta receptor; 5-HT1B; HTR1DB; 5-HT1DB;
Gene ID
MIM
UniProt ID
P28222
Chromosome Location
6q13
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Monoamine GPCRs, organism-specific biosystem;
Function
G-protein coupled receptor activity; drug binding; receptor activity; serotonin binding; serotonin receptor activity; signal transducer activity;

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