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Human HCAR2-FLAG Stable Cell Line-CHO

See other products for HCAR2
Cat.No.
CSC-RG0337
Background
GPR109A (HM74A, PUMA-G or niacin receptor 1) is a high-affinity receptor for nicotinic acid (niacin), and is highly expressed in adipocytes, lung, macrophages, dendritic cells, microglia and neutrophils. GPR109A in adipocytes is likely to be involved in niacinmediated inhibition of lipolysis, reduction of serum free fatty acids and triglycerides as well as elevation of high density lipoproteins. GPR109A also serves important functions in the immune system. GPR109A on Langerhans cells in the skin also mediates niacin-induced cutaneous flushing, one of the major side effects of niacin, via the massive production of prostaglandins PGD2 and PGE2 in a ligand-dependent fashion.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
HCAR2
Synonyms
HCAR2; hydroxycarboxylic acid receptor 2; G protein coupled receptor 109A , GPR109A; HCA2; HM74A; niacin receptor 1; NIACR1; Puma g; PUMAG; nicotinic acid receptor; G protein-coupled receptor 109A; G-protein coupled receptor 109A; G protein-coupled receptor HM74a; G-protein coupled receptor HM74A; hydroxy-carboxylic acid receptor 2; HM74a; HM74b; Puma-g; GPR109A;
Gene ID
MIM
UniProt ID
Q8TDS4
Chromosome Location
12q24.31
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem;
Function
G-protein coupled purinergic nucleotide receptor activity; nicotinic acid receptor activity; receptor activity; signal transducer activity;
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Cat#
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Titer
Product Size
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AD07361Z
>1x 10^9 vp/ml
1 x 0.2 ml
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Cat#
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Size/Form
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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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