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Human H3F3A/Galpha15 Stable Cell Line-Chem-3

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Cat.No.
CSC-RG0677
Background
The histamine H3 receptor was defined pharmacologically to be a presynaptic histamine receptor that binds selectively to R-(alpha)-methylhistamine and inhibits neurotransmitter release in the central and peripheral nervous systems. Molecular cloning of the H3 receptor confirmed it to be a Gi-coupled receptor widely expressed at high levels in the brain. H3 presents a potential therapeutic target for disorders of the central nervous system involving attention, cognition and feeding.
Growth Properties
Adherent
Host Cell
Chem-3
Ship
Dry ice
Gene Information
Official Symbol
H3F3A
Synonyms
H3F3A; H3 histone, family 3A; H3F3; histone H3.3; H3.3A; H3F3B; MGC87782; MGC87783;
Gene ID
MIM
UniProt ID
P84243
Chromosome Location
1q42.12
Pathway
Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Gene Expression, organism-specific biosystem; Hemostasis, organism-specific biosystem;

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