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Human GRPR-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0186
Background
The bombesin receptor BB2 (or gastrin-releasing peptide receptor GRPR) is responsible for many physiological actions such as inhibition of feeding, smooth muscle contraction, exocrine and endocrine secretions, thermoregulation, blood pressure and sucrose regulations, and cell growth. BB2 is expressed in the brain, as well as in colon, lung, and prostate cancer cells. The development of potent receptor antagonists that block BB2 receptor responses has potential for new therapeutic treatments in cancer.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
GRPR
Synonyms
GRPR; gastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor;
Gene ID
MIM
UniProt ID
P30550
Chromosome Location
Xp22.2
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
G-protein coupled peptide receptor activity; bombesin receptor activity; neuropeptide binding; receptor activity; signal transducer activity;

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