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Human GRM8-FLAG Stable Cell Line-HEK293T

Cat.No.
CSC-RG0314
Abbr
HEK293T-HuGRM8-FLAG
Alias
GRM8,GLUR8,GPRC1H,mGlu8,MGLUR8,FLJ41058
Growth Properties
Adherent
Host Cell
HEK293T
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
The metabotropic glutamate receptors (mGluRs) have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group II and group III mGluRs are linked to the inhibition of the cyclic AMP cascade, but differ in agonist selectivity. Group III agonists include L-2-amino-4-phosphonobutyrate (L-AP4) and L-serine-O-phosphate. The human mGluR8 protein shares 67 to 70% sequence similarity with mGluR4 and mGluR7 and 99% amino acid identity with mouse mGluR8.

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