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Human GRM7-FLAG Stable Cell Line-HEK293T Galphaqi5

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Cat.No.
CSC-RG0311
Background
The metabotropic glutamate receptors (mGluRs) are divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms and pharmacological properties. Group II and group III mGluRs are linked to inhibition of the cyclic AMP cascade, but differ in their agonist selectivity. mGluR7 is a member of Group III. Immunohistochemistry and in situ hybridization showed that mGluR7 expresses in various sites in the nervous system.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T Galphaqi5
Ship
Dry ice
Gene Information
Official Symbol
GRM7
Synonyms
GRM7; glutamate receptor, metabotropic 7; metabotropic glutamate receptor 7; GLUR7; GPRC1G; mGlu7; MGLUR7; MGLU7; FLJ40498;
Gene ID
MIM
UniProt ID
Q14831
Chromosome Location
3p26-p25
Pathway
Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; PDZ domain binding; adenylate cyclase inhibitor activity; calcium channel regulator activity; calcium ion binding; glutamate binding; glutamate receptor activity; group III metabotropic glutamate receptor activity; receptor activity; serine binding; signal transducer activity; voltage-gated calcium channel activity;

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