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Human GRM6-FLAG Stable Cell Line-HEK293T Galphaqi5

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Cat.No.
CSC-RG0309
Background
The metabotropic glutamate receptors (mGluRs) are divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacological properties. Group II and group III mGluRs are linked to inhibition of the cyclic
AMP cascade, but differ in their agonist selectivity. mGluR6 is a member of Group III. It mainly expresses in on-bipolar cells in retina.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T Galphaqi5
Ship
Dry ice
Gene Information
Official Symbol
GRM6
Synonyms
GRM6; glutamate receptor, metabotropic 6; metabotropic glutamate receptor 6; GPRC1F; mGlu6; MGLUR6; CSNB1B; DKFZp686H1993;
Gene ID
MIM
UniProt ID
O15303
Chromosome Location
5q35
Pathway
Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; adenylate cyclase inhibiting G-protein coupled glutamate receptor activity; glutamate receptor activity; receptor activity; signal transducer activity;

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