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Human GRM5-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0308
Background
The metabotropic glutamate receptors (mGluRs) are divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacological properties. Group II and group III mGluRs are linked to inhibition of the cyclic AMP cascade, but differ in their agonist selectivity. mGluR5 is a member of Group I. It mainly expresses the brain although its precise role in various cortical functions remains unclear.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
GRM5
Synonyms
GRM5; glutamate receptor, metabotropic 5; metabotropic glutamate receptor 5; GPRC1E; mGlu5; MGLUR5; metabotropic glutamate receptor 5 variant F; metabotropic glutamate receptor 5 variant G; metabotropic glutamate receptor 5 variant H;
Gene ID
MIM
UniProt ID
P41594
Chromosome Location
11q14.3
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem;
Function
A2A adenosine receptor binding; G-protein coupled receptor activity; G-protein coupled receptor activity; glutamate receptor activity; receptor activity; signal transducer activity;

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