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Human GRM4-FLAG Stable Cell Line-HEK293T

See other products for GRM4
Cat.No.
CSC-RG0307
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors, which are G protein-coupled receptors, have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms and pharmacologic properties. Group II and group III receptors are linked to the inhibition of the cyclic AMP cascade, but differ in their agonist selectivity. Group III agonists include L-2-amino-4-phosphonobutyrate (L-AP4) and L-serine-O-phosphate.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
GRM4
Synonyms
GRM4; glutamate receptor, metabotropic 4; metabotropic glutamate receptor 4; GPRC1D; mGlu4; MGLUR4; MGC177594;
Gene ID
MIM
UniProt ID
Q14833
Chromosome Location
6p21.3
Pathway
Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; G-protein coupled receptor activity; glutamate receptor activity; receptor activity; signal transducer activity;
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AD07168Z
>1x 10^9 vp/ml
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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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