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Human GRM2-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0303
Background
The neurotransmitter L-glutamate interacts with both ionotropic and metabotropic receptors. The metabotropic glutamate receptors (mGluRs), which are G protein-coupled receptors, have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group II and group III mGluRs are linked to the inhibition of the cyclic AMP cascade, but differ in their agonist selectivity. The mGluR2 is a member of group II metabotropic glutamate receptors.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
GRM2
Synonyms
GRM2; glutamate receptor, metabotropic 2; metabotropic glutamate receptor 2; GPRC1B; mGlu2; MGLUR2; glutamate receptor homolog; glutamate metabotropic receptor 2; GLUR2;
Gene ID
MIM
UniProt ID
Q14416
Chromosome Location
3
Pathway
Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem; Cocaine addiction, organism-specific biosystem; Cocaine addiction, conserved biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem;
Function
G-protein coupled receptor activity; calcium channel regulator activity; glutamate receptor activity; group II metabotropic glutamate receptor activity; receptor activity; signal transducer activity;

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