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Human GR (LBD)-GAL4 (DBD) Stable Cell Line-HEK 293T(UAS-bla)

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Cat.No.
CSC-RN0006
Background
The glucocorticoid receptor (GR) is a validated drug target for inflammation. GR targets such as dexamethasone are clinically available as anti-inflammatory drugs.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK 293T
Ship
Dry ice
Gene Information
Official Symbol
NR3C1
Synonyms
NR3C1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); GRL, nuclear receptor subfamily 3, group C, member 1; glucocorticoid receptor; GR; glucocorticoid nuclear receptor variant 1; GCR; GRL; GCCR;
Gene ID
UniProt ID
P04150
Chromosome Location
5q31-q32
Pathway
Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem;
Function
Hsp70 protein binding; Hsp90 protein binding; chromatin binding; double-stranded DNA binding; glucocorticoid receptor activity; metal ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity; receptor activity; receptor tyrosine kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; zinc ion binding;

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