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Human GPR39/Galpha15 Stable Cell Line-HEK293

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Cat.No.
CSC-RG0716
Background
GPR39 is a 7TM protein related to the G protein-coupled receptors for the gastrointestinal peptides ghrelin and motilin. Although GPCR39 has been reported to be a receptor for the peptide obestatin, GPR39 has been more thoroughly characterized as a receptor for Zn2+, as well as Cu2+ and Ni2+. Studies on GPR39-null mice implicate GPR39 in the control of insulin secretion, thereby indicating its potential as a target for treatment of diabetes.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
GPR39
Synonyms
GPR39; MGC149541; G protein-coupled receptor 39; G-protein coupled receptor 39
Gene ID
MIM
UniProt ID
O43194
Chromosome Location
2q21-q22
Pathway
Class A/1 (Rhodopsin-like receptors); GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Signal Transduction; Signaling by GPCR
Function
G-protein coupled receptor activity; metal ion binding

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