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Human GPBAR1/beta-Arrestin Stable Cell Line-U2OS

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Cat.No.
CSC-RG1507
Background
The G protein-coupled bile acid receptor GPBAR1 (or GPR131) mediates bile acids-induced rapid elevation of intracellular cAMP levels. It is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
U2OS
Ship
Dry ice
Gene Information
Official Symbol
GPBAR1
Synonyms
GPBAR1; BG37; GPCR19; GPR131; M-BAR; TGR5; G protein-coupled bile acid receptor 1; G-protein coupled bile acid receptor 1; hBG37; hGPCR19; membrane bile acid receptor; G-protein coupled receptor GPCR19; membrane-type receptor for bile acids; G-protein coupled bile acid receptor BG37
Gene ID
MIM
UniProt ID
Q8TDU6
Chromosome Location
2q35
Pathway
Class A/1 (Rhodopsin-like receptors); GPCR ligand binding; Signal Transduction; Signal by GPCR; G alpha (s) signalling events; GPCR downstream signaling
Function
G-protein coupled receptor activity

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