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Human GPBAR1-FLAG Stable Cell Line-CHO

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Cat.No.
CSC-RG0181
Background
The G protein-coupled bile acid receptor GPBAR1 (or GPR131) mediates bile acids-induced rapid elevation of intracellular cAMP levels. It is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GPBAR1
Synonyms
GPBAR1; BG37; GPCR19; GPR131; M-BAR; TGR5; G protein-coupled bile acid receptor 1; G-protein coupled bile acid receptor 1; hBG37; hGPCR19; membrane bile acid receptor; G-protein coupled receptor GPCR19; membrane-type receptor for bile acids; G-protein coupled bile acid receptor BG37
Gene ID
MIM
UniProt ID
Q8TDU6
Chromosome Location
2q35
Pathway
Class A/1 (Rhodopsin-like receptors); GPCR ligand binding; Signal Transduction; Signal by GPCR; G alpha (s) signalling events; GPCR downstream signaling
Function
G-protein coupled receptor activity

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