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Human GNRHR/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1285
Background
Gonadotropin-releasing hormone receptor (GnRHR) is a receptor for gonadotropin-releasing hormone (GnRH), also known as luteinizing hormonereleasing hormone (LHRH) and prolactin release-inhibiting factor (PIF). GnRHR is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Gametes and preimplantation embryos also express GnRH and GnRHR. Binding of GnRH to GnRHR causes the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from gonadotropic cells of the anterior pituitary. Mutations in GnRHR may cause hypogonadotropic hypogonadism and may be associated with anosmia.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GNRHR
Synonyms
GNRHR; gonadotropin-releasing hormone receptor; GRHR; LHRHR; gnRH-R; gnRH receptor; luliberin receptor; type I GnRH receptor; leutinizing-releasing hormone receptor; leutinizing hormone releasing horomone receptor; gonadotropin-releasing hormone (type 1) receptor 1; LRHR; GNRHR1;
Gene ID
MIM
UniProt ID
P30968
Chromosome Location
4q21.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; GnRH signaling pathway, organism-specific biosystem; GnRH signaling pathway, conserved biosystem;
Function
gonadotropin-releasing hormone receptor activity; growth hormone-releasing hormone receptor activity; receptor activity; signal transducer activity;

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