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Human GLP2R/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1506
Background
GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member related to glucagon receptor and GLP1 receptor. Glucagon like peptide 2 receptor is expressed in SNC and gut. GLP2R transduces the biological actions of GLP-2, a 33 aminoacid peptide produced by the intestinal endocrine L cell and by various neurons in the central nervous system. Intestinal GLP-2 is co-secreted along with GLP-1 upon nutrient ingestion. GLP-2 produces several actions such as including intestinal growth, enhancement of intestinal function, reduction in bone breakdown and neuroprotection.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GLP2R
Synonyms
GLP2R; glucagon-like peptide 2 receptor; GLP-2R; GLP-2-R; GLP-2 receptor;
Gene ID
MIM
UniProt ID
O95838
Chromosome Location
17p13.3
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
G-protein coupled receptor activity; glucagon receptor activity; receptor activity; signal transducer activity;

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