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Human GLP2R/Galpha15 Stable Cell Line-Chem-11

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Cat.No.
CSC-RG0668
Background
Glucagon-like peptide 2 (GLP-2) is a 33 amino acid peptide secreted by intestinal endocrine L cells in response to nutrient uptake. GLP-2 exerts multiple effects on intestinal physiology, including promotion of epithelial cell growth and survival to increase intestinal mass, increasing nutrient absorption capacity, and inhibition of intestinal inflammation. The GLP-2 Receptor is a class B GPCR belonging to the glucagon/secretin family of receptors, and as with the other members of the family, activation of the GLP-2 receptor results in increased intracellular cAMP.
Growth Properties
Adherent
Host Cell
Chem-11
Ship
Dry ice
Gene Information
Official Symbol
GLP2R
Synonyms
GLP2R; glucagon-like peptide 2 receptor; GLP-2R; GLP-2-R; GLP-2 receptor;
Gene ID
MIM
UniProt ID
O95838
Chromosome Location
17p13.3
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
G-protein coupled receptor activity; glucagon receptor activity; receptor activity; signal transducer activity;

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