Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


Human GLP1R/Clytin Stable Cell Line-HEK293

See other products for GLP1R
Cat.No.
CSC-RG0666
Background
Glucagon-like peptide-I (GLP-1), a member of the glucagon-secretin peptide family, is secreted from L-cells of the small intestine and binds to a class B (class 2) G protein-coupled receptor. The GLP-1 receptor is expressed in pancreatic beta cells and upon binding to GLP-1, it couples to Gs to increase cAMP levels and insulin secretion. In addition, GLP-1 has been shown to delay gastric emptying and regulate appetite. Therefore, the GLP-1 receptor represents an important therapeutic target for type II diabetes. In addition, the degradation-resistant analog of GLP-1, exanatide, is used clinically in combination with other glucose-lowering drugs to control type II diabetes.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
GLP1R
Synonyms
GLP1R; glucagon-like peptide 1 receptor; GLP-1R; GLP-1-R; GLP-1 receptor; MGC138331;
Gene ID
MIM
UniProt ID
P43220
Chromosome Location
6p21
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem;
Function
G-protein coupled peptide receptor activity; glucagon receptor activity; peptide hormone binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity;
Related Products
Cat#
Product Name
Host Cell
Gene Symbol
Species
Price
CSC-SC006329
HEK293 ,CHO, etc.
GLP1R
Human
CSC-RG0487
CHO-K1
GLP1R
Human
Cat#
Product Name
Titer
Product Size
Species
Price
AD00179Z
1x10^10~1x10^11 PFU/ml
1 x 0.2 ml
Human
AD06820Z
>1x 10^9 vp/ml
1 x 0.2 ml
Human
Cat#
Product Name
Size/Form
Species
Price

Related Services

Quick Inquiry

Please input "biogene" as verification code.
GLP1R Related Products
Contact us to order
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828
Email: info@creative-biogene.com
CBpromise

24x7 CUSTOMER SERVICE

CONTACT US TO ORDER

;

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2018 Creative Biogene. All Rights Reserved.