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Human GIPR/Gs Stable Cell Line-CHO

See other products for GIPR
Cat.No.
CSC-RG0565
Background
Gastric inhibitory polypeptide (GIP) is a 42-amino acid polypeptide synthesized by K-cells of the duodenum and small intestine. GIP’s principle physiological action is to stimulate insulin secretion from pancreatic beta-cells in a glucose-dependent manner. Additional effects of GIP have been described, including effects on lipid metabolism, stimulation of glucagons and somatostatin release. GIP exerts its effects by binding to its specific receptor, the GIP receptor which belongs to the VIP/glucagon/secretin family of G protein-coupled receptors and is positively coupled to adenylyl cyclase but not to phospholipase C.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GIPR
Synonyms
GIPR; gastric inhibitory polypeptide receptor; GIP-R; glucose-dependent insulinotropic polypeptide receptor; PGQTL2; MGC126722;
Gene ID
UniProt ID
P48546
Chromosome Location
19q13.2-q13.3
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
gastric inhibitory peptide receptor activity; peptide hormone binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity;
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>1x 10^9 vp/ml
1 x 0.2 ml
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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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