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Human GHSR-FLAG Stable Cell Line-CHO

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Cat.No.
CSC-RG0266
Background
The ghrelin receptor is the target of growth hormone secretagogues, a class of synthetic peptide and non-peptide compounds that stimulate growth hormone (GH) release from the anterior pituitary. Ghrelin, the endogenous ligand for the ghrelin receptor, is predominantly secreted from X/A-like cells within the gastric mucosa and may be the source of the majority of circulating plasma ghrelin. Ghrelin stimulates gastric acid secretion and motility, and may have significant effects on appetite and energy. It is not only important for the acute regulation of food intake but also plays an important role in the regulation of long term energy homoeostasis. Ghrelin has a number of actions in cardiovascular system, consistent with the localization of receptors to cardiovascular tissue.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GHSR
Synonyms
GHSR; growth hormone secretagogue receptor; growth hormone secretagogue receptor type 1; GHRP; GHS-R; ghrelin receptor; GH-releasing peptide receptor;
Gene ID
MIM
UniProt ID
Q92847
Chromosome Location
3q26.31
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; growth hormone secretagogue receptor activity; growth hormone-releasing hormone receptor activity; peptide hormone binding; receptor activity; signal transducer activity;

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