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Human GHRHR/Gs Stable Cell Line-CHO

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Cat.No.
CSC-RG0500
Background
Growth hormone-releasing hormone (GHRH), acting through the GHRH receptor GHRHR, plays a pivotal role in the regulation of GH synthesis and secretion in the pituitary. The isolated cDNA of the GHRHR predicted a 423-amino acid protein that has 7 putative transmembrane domains, characteristic of G proteincoupled receptors. It is a member of the secretin family of G protein-coupled
receptors and has 47%, 42%, 35%, and 28% identity with receptors for vasoactive intestinal peptide, secretin, calcitonin and parathyroid hormone, respectively.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GHRHR
Synonyms
GHRHR; growth hormone releasing hormone receptor; growth hormone-releasing hormone receptor; GRF receptor; GHRH receptor; GRFR; GHRFR; IGHD1B;
Gene ID
MIM
UniProt ID
Q02643
Chromosome Location
7p14
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem;
Function
G-protein coupled receptor activity; growth factor binding; growth hormone-releasing hormone receptor activity; growth hormone-releasing hormone receptor activity; peptide hormone binding; protein binding; receptor activity; signal transducer activity;

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