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Human GCGR Stable Cell Line-CHO-K1/Gα15

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Cat.No.
CSC-RG1673
Background
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism.
Host Cell
CHO-K1/Gα15
Ship
Dry Ice
Antigen Gene Information
Official Symbol
GCGR
Synonyms
GCGR; glucagon receptor; GGR; GL-R; FLJ97182; MGC138246;
GeneID
MIM
UniProt ID
P47871
Chromosome Location
17q25
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon signaling in metabolic regulation, organism-specific biosystem;
Function
glucagon receptor activity; guanyl-nucleotide exchange factor activity; peptide hormone binding; receptor activity; signal transducer activity;

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