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Human GALR1/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1500
Background
The diverse physiological effects of Galanin, a biologically active neuropeptide, are mediated through cell surface G protein-coupled receptors. To date, three galanin receptor subtypes, GAL1, GAL2 and GAL3, have been cloned. Galanin, widely distributed in the central and peripheral nervous systems and the endocrine systems, binds to galanin receptors to induce several regulatory functions in neuronal cells, including neuroregeneration, control of endocrine and exocrine secretions, and modulation of sensory and behavioral functions. Galanin agonists have been shown to have therapeutic application in treatment of chronic pain; galanin antagonists have therapeutic potential in treatment of Alzheimer"s disease, depression, and feeding disorders.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
GALR1
Synonyms
GALR1; galanin receptor 1; GALNR, GALNR1; galanin receptor type 1; GAL1-R; GALR-1; GALNR; GALNR1;
Gene ID
MIM
UniProt ID
P47211
Chromosome Location
18q23
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; galanin receptor activity; neuropeptide binding; receptor activity; signal transducer activity;

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