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Human FPR2 Stable Cell Line-CHO-K1/Gα15

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Cat.No.
CSC-RG1682
Background
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotacticfactors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via aG-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R couldresult in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4(leukotriene B4)
Host Cell
CHO-K1/Gα15
Ship
Dry Ice
Antigen Gene Information
Official Symbol
FPR2
Synonyms
FPR2; formyl peptide receptor 2; formyl peptide receptor like 1 , FPRL1; N-formyl peptide receptor 2; ALXR; FMLP R II; FMLPX; FPR2A; FPRH2; HM63; LXA4R; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related); FPRH1; FPRL1; FMLP-R-II;
GeneID
MIM
UniProt ID
P25090
Chromosome Location
19q13.3-q13.4
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Formyl peptide receptors bind formyl peptides and many other ligands, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
G-protein coupled receptor activity; N-formyl peptide receptor activity; receptor activity; signal transducer activity;

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