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Human FFAR3/Galpha15 Stable Cell Line-Chem-4

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Cat.No.
CSC-RG0658
Background
GPR41 is a GPCR that, along with GPR43, is activated by short chain carboxylic acids formate, acetate, proprionate, butyrate and pentanoate. Binding of these ligands to GPR41 selectively activates Gi to inhibit cAMP accumulation. Expression of GPR41 is prominent in adipose tissue, increases during differentiation of cultured adipocytes, and allows short chain carboxylic acids to stimulate leptin synthesis in adipocytes.
Growth Properties
Adherent
Host Cell
Chem-4
Ship
Dry ice
Gene Information
Official Symbol
FFAR3
Synonyms
FFAR3; free fatty acid receptor 3; G protein coupled receptor 41 , GPR41; FFA3R; G protein-coupled receptor 41; G-protein coupled receptor 41; GPR41;
Gene ID
MIM
UniProt ID
O14843
Chromosome Location
19q13.1
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Free fatty acid receptors, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function
G-protein coupled receptor activity; lipid binding; receptor activity; signal transducer activity;

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