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Human FFAR2 Stable Cell Line-CHO

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Cat.No.
CSC-RG0862
Background
GPR43 is a member of the free fatty acid G protein-coupled receptor family and is activated by short-chain fatty acids (SCFAs). Expression analysis shows that GPR43 is expressed selectively in leukocytes and to a lesser extent, in spleen. Upon activation by propionate or acetate, GPR43 has been shown to mobilize intracellular calcium in both recombinant systems as well as in human granulocytes.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
13 passages (6 weeks of continuous culture)
Ship
Dry ice
Gene Information
Official Symbol
FFAR2
Synonyms
FFAR2; FFA2R; GPR43; free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; free fatty acid activated receptor 2
Gene ID
MIM
UniProt ID
O15552
Chromosome Location
19q13.1
Pathway
Class A/1 (Rhodopsin-like receptors); Free fatty acid receptors; G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Gastrin-CREB signalling pathway via PKC and MAPK;
Function
G-protein coupled receptor activity; lipid binding

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