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Human F2RL3/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1494
Background
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
F2RL3
Synonyms
F2RL3; coagulation factor II (thrombin) receptor-like 3; proteinase-activated receptor 4; PAR4; proteinase activated receptor 4; PAR-4; thrombin receptor-like 3; protease-activated receptor-4; proteinase-activated receptor-4; coagulation factor II receptor-like 3;
Gene ID
MIM
UniProt ID
Q96RI0
Chromosome Location
19p12
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Hemostasis, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity; thrombin receptor activity;

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