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Human F2RL1/beta-Arrestin Stable Cell Line-HEK293

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Cat.No.
CSC-RG1492
Background
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
F2RL1
Synonyms
F2RL1; GPR11; PAR2; coagulation factor II (thrombin) receptor-like 1; G protein-coupled receptor-11; G-protein coupled receptor 11; PAR-2; coagulation factor II receptor-like 1; protease-activated receptor 2; proteinase-activated receptor 2; proteinase-activated receptor-2; thrombin receptor-like 1
Gene ID
MIM
UniProt ID
P55085
Chromosome Location
5q13
Pathway
African trypanosomiasis;

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