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Human EDNRB/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1490
Background
The endothelins and their receptors are referred as the endothelin (ET) axis and this axis has been implicated in diverse tumours.
Endothelin B receptor (ETB) may oppose cancer advance by helping apoptosis and clearing ET-1; however, it has recently been involved in the progress of some tumour as melanomas or oligodendrogliomas. The multigenic disorder, Hirschsprung disease type 2, is due to mutation in endothelin receptor type B gene.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
EDNRB
Synonyms
EDNRB; endothelin receptor type B; HSCR, HSCR2; endothelin B receptor; ETB; endothelin receptor non-selective type; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2;
Gene ID
MIM
UniProt ID
P24530
Chromosome Location
13q22
Pathway
Arf6 trafficking events, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Endothelins, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled receptor activity; endothelin receptor activity; endothelin receptor activity; endothelin receptor activity; peptide hormone binding; receptor activity; signal transducer activity;

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