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Human DRD5/Gs Stable Cell Line-CHO

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Cat.No.
CSC-RG0518
Background
The human dopamine receptor D5 is a D1-like receptor and its activation stimulates adenylyl cyclase activity. It has a 10-fold higher affinity for dopamine than the D1 receptor. The D5 receptor is expressed in neurons in the limbic regions of the brain, and has been implicated in ADHD and addiction disorders.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
DRD5
Synonyms
DRD5; dopamine receptor D5; DRD1L2; D(1B) dopamine receptor; DRD1B; dopamine D5 receptor; dopamine receptor D1B; d dopamine receptor; D1beta dopamine receptor; DBDR; MGC10601;
Gene ID
UniProt ID
P21918
Chromosome Location
4p16.1
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Dopamine receptors, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem;
Function
G-protein alpha-subunit binding; G-protein coupled receptor activity; dopamine binding; dopamine receptor activity; dopamine receptor activity, coupled via Gs; drug binding; receptor activity; signal transducer activity;

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