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Human DRD4/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1477
Background
The human dopamine receptor D4 is a D2-like receptor that inhibits adenylyl cyclase activity and activates K+ channels. D4 receptor antagonists show great potential in the treatment of human personality and psychiatric disorders, such as ADHD (Attention deficit hyperactivity disorder), schizophrenia, alcoholism, and drug addiction.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
DRD4
Synonyms
DRD4; dopamine receptor D4; D dopamine receptor; dopamine D4 receptor; D(2C) dopamine receptor; seven transmembrane helix receptor; D4DR;
Gene ID
MIM
UniProt ID
P21917
Chromosome Location
11p15.5
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Dopamine receptors, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled receptor activity; SH3 domain binding; dopamine binding; dopamine receptor activity; dopamine receptor activity, coupled via Gi/Go; dopamine receptor activity, coupled via Gi/Go; drug binding; potassium channel regulator activity; protein binding; receptor activity; signal transducer activity;

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