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Human CYSLTR1-FLAG Stable Cell Line-HEK293T

Cat.No.
CSC-RG0281
Abbr
HEK293T-HuCYSLTR1-FLAG
Alias
CYSLTR1,CysLT(1),CysLT1,CYSLT1R,HG55,CYSLT1,CYSLTR,HMTMF81
Growth Properties
Adherent
Host Cell
HEK293T
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
CysLTR1 (Cysteinyl leukotriene receptor 1) is also known as LTD4 receptor (leukotriene D4 receptor), HG55 or HMTMF81. It is a receptor for cysteinyl leukotrienes and has highest affinity to leukotriene D4 (LTD4). The receptor mediates contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung caused by LTD4. Several antagonists, such as montelukast (Singulair), zafirlukast (Accolate) and pranlukast (Onon), are used in the treatment of asthma.

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