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Human CYSLTR1-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0281
Background
CysLTR1 (Cysteinyl leukotriene receptor 1) is also known as LTD4 receptor (leukotriene D4 receptor), HG55 or HMTMF81. It is a receptor for cysteinyl leukotrienes and has highest affinity to leukotriene D4 (LTD4). The receptor mediates contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung caused by LTD4. Several antagonists, such as montelukast (Singulair), zafirlukast (Accolate) and pranlukast (Onon), are used in the treatment of asthma.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
CYSLTR1
Synonyms
CYSLTR1; cysteinyl leukotriene receptor 1; CysLT; CysLT1; CYSLT1R; LTD4 receptor; G-protein coupled receptor HG55; cysteinyl leukotriene D4 receptor; HG55; CYSLT1; CYSLTR; HMTMF81; MGC46139;
Gene ID
MIM
UniProt ID
Q9Y271
Chromosome Location
Xq13-q21
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; Endothelins, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
leukotriene receptor activity; receptor activity; signal transducer activity;

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