Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

Human CXCR3/Apoaequorin Stable Cell Line-CHO

See other products for CXCR3
Cat.No.
CSC-RG1267
Background
CXCR3 is a 7-TM GPCR that is selective for the CXC chemokines IP10, I-TAC and MIG. Binding of IP10 and MIG to CXCR3 induces Ca2+ mobilization, chemotaxis and inflammatory responses of T lymphocytes, and also act as potent inhibitors of angiogenesis. CXCR3 is highly expressed in IL-2-activated T lymphocytes in vitro, and in T lymphocytes present in inflamed tissues in rheumatoid arthritis and multiple sclerosis. In vivo, neutralization of CXCR3 inhibits experimentally induced type I diabetes, peritonitis, and post-lung transplantation bronchiolitis obliterans syndrome.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CXCR3
Synonyms
CXCR3; chemokine (C-X-C motif) receptor 3; G protein coupled receptor 9 , GPR9; C-X-C chemokine receptor type 3; CD183; CKR L2; CMKAR3; IP10 R; MigR; CXC-R3; CXCR-3; Mig receptor; IP10 receptor; IP-10 receptor; G protein-coupled receptor 9; chemokine (C-X-C) receptor 3; interferon-inducible protein 10 receptor; GPR9; CD182; Mig-R; CKR-L2; IP10-R;
Gene ID
MIM
UniProt ID
P49682
Chromosome Location
Xq13
Pathway
CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function
C-X-C chemokine receptor activity; G-protein coupled receptor activity; chemokine binding; chemokine receptor activity; receptor activity; signal transducer activity;

Quick Inquiry

Please input "biogene" as verification code.

CXCR3 Related Products

Transfected Stable Cell Lines

By Gene symbol(12)
+Expand
By Species(12)
+Expand

Contact Us

USA

Europe

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER