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Human CXCR1 Stable Cell Line-CHO-K1/Gα15

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Cat.No.
CSC-RG1660
Background
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Host Cell
CHO-K1/Gα15
Ship
Dry Ice
Antigen Gene Information
Official Symbol
CXCR1
Synonyms
CXCR1; chemokine (C-X-C motif) receptor 1; CMKAR1, IL8RA, interleukin 8 receptor, alpha; C-X-C chemokine receptor type 1; CD181; CDw128a; CKR 1; CXC-R1; CXCR-1; IL-8R A; IL-8 receptor type 1; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; high affinity interleukin-8 receptor A; C-C; CD128; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; C-C-CKR-1;
GeneID
MIM
UniProt ID
P25024
Chromosome Location
2q35
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem;
Function
G-protein coupled receptor activity; chemokine receptor activity; interleukin-8 binding; interleukin-8 receptor activity; receptor activity; signal transducer activity;

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