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Human CRHR2/Gs Stable Cell Line-CHO

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Cat.No.
CSC-RG0473
Background
Corticotropin releasing hormone receptor 2 is the gene encodes a protein that is one of two Corticotropin releasing hormone receptors (CRHRs), also termed as CRFRs. The Corticotropin releasing hormone receptor family is a group of G-coupled receptors whose principal ligand is the corticocotropin releasing hormone (CRHR or CRF). CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamicpituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioural responses to stress and immune challenge.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CRHR2
Synonyms
CRHR2; corticotropin releasing hormone receptor 2; corticotropin-releasing factor receptor 2; CRF RB; CRF2; HM CRF; CRH-R2; CRF2 receptor, beta isoform; CRFR2; CRF-RB; HM-CRF;
Gene ID
MIM
UniProt ID
Q13324
Chromosome Location
7p21-p15
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
corticotrophin-releasing factor receptor activity; protein binding; receptor activity; signal transducer activity;

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