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Human CRHR1 Stable Cell Line-HEK293T Gαqi5

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Cat.No.
CSC-RG1728
Background
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and upstream GeneID:401884 (ADP-ribosylation factor 3 pseudogene), and the readthrough transcripts encode isoforms that share similarity with the products of this gene.
Host Cell
HEK293T Gαqi5
Ship
Dry ice
Antigen Gene Information
Official Symbol
CRHR1
Synonyms
CRF1; CRHR; CRF-R; CRFR1; CRF-R1; CRFR-1; CRH-R1; CRHR1L; CRHR1f; CRF-R-1; CRH-R-1; CRH-R1h
GeneID
MIM
UniProt ID
P34998
Chromosome Location
17q12-q22
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Long-term depression, organism-specific biosystem;
Function
corticotrophin-releasing factor receptor activity; protein binding;

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