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Human CNR2/beta-Arrestin Stable Cell Line-HEK293

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Cat.No.
CSC-RG1454
Background
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Cannabinoid receptor 2(CNR2) and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dosedependent, stereoselective, and pertussis toxinsensitive manner. These proteins have been found to be involved in the cannabinoidinduced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
CNR2
Synonyms
CNR2; cannabinoid receptor 2 (macrophage); cannabinoid receptor 2; CB2; testis-dominant CNR2 isoform CB2; CX5; CB-2;
Gene ID
MIM
UniProt ID
P34972
Chromosome Location
1p
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
cannabinoid receptor activity; receptor activity; signal transducer activity;

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