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Human CNR2/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0485
Background
The CB2 cannabinoid receptor is expressed primarily in cells of the peripheral immune system and is a target for cannabinoids (Munro et al., 1993; Gerard et al., 1991), the psychoactive ingredients of marijuana. Other members of the cannabinoid family of receptors include the CB1 cannabinoid receptor, which is expressed primarily in brain, and GPR55 (Ryberg, 2007). When activated, the CB2 receptor inhibits adenylate cyclase by coupling through Gi.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CNR2
Synonyms
CNR2; cannabinoid receptor 2 (macrophage); cannabinoid receptor 2; CB2; testis-dominant CNR2 isoform CB2; CX5; CB-2;
Gene ID
MIM
UniProt ID
P34972
Chromosome Location
1p
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
cannabinoid receptor activity; receptor activity; signal transducer activity;

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