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Human CNR1/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0495
Background
The CB1 cannabinoid receptor is expressed primarily in brain and is a target for cannabinoids (Matsuda et al., 1990, Gerard et al., 1991), the psychoactive ingredients of marijuana. Other members of the cannabinoid family of receptors include the CB2 cannabinoid receptor, which is expressed primarily in the periphery, and GPR55 (Ryberg, 2007). When activated, the CB1 receptor inhibits adenylate cyclase through Gi. The CB1 receptor plays a significant role in modulation of food intake (Cota, 2007).
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CNR1
Synonyms
CNR1; cannabinoid receptor 1 (brain); CNR; cannabinoid receptor 1; CANN6; CB R; CB1; CB1A; CB1K5; central cannabinoid receptor; CB-R; CB1R;
Gene ID
MIM
UniProt ID
P21554
Chromosome Location
6q14-q15
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; N-cadherin signaling events, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
cannabinoid receptor activity; drug binding; receptor activity; signal transducer activity;

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